Physicians who follow some of their country's sharpest elderly patients noticed a pattern in what those patients drink — and large studies in the U.S. and the U.K. have since found links worth knowing about.
At 84, retired U.S. Army Major Frank Okafor still recites his unit's radio frequencies from 1971 without missing a digit. He remembers faces, names, and conversations from half a century ago with an ease that unnerves younger people around him. His physician, who has treated him for nearly 20 years, calls him extraordinary. Frank disagrees.
"I just never drank the stuff everyone else was drinking," he says.
To a casual observer, that sounds like the kind of thing any 84-year-old might say. But to some physicians in Japan — the country whose Okinawa prefecture has long been studied for one of the highest proportions of centenarians in the world[1] — it touches a question researchers are taking seriously: how much do everyday habits shape the way our memory ages?
"My patients with the sharpest minds at 80 and 90 are not the ones who take the most supplements. They are the ones who removed certain things from their lives decades ago."
— Dr. K. Morita, Geriatric Medicine, Osaka
Over many years of practice, Dr. Morita noticed that the patients who scored highest on cognitive assessments did not share an unusual medication, a single genetic marker, or one exercise routine. What many of them did share was a set of everyday habits — including avoiding three drinks that a lot of people consume every day. His observation is anecdotal. But each of those three drinks has since been examined in large, peer-reviewed studies.
The 3 Drinks Researchers Have Linked to Memory and Brain Health
1
Sugary Beverages — Including Bottled Fruit Juice
In a study of about 4,000 adults from the Framingham Heart Study, published in the journal
Alzheimer's & Dementia, people who drank more sugary beverages had lower total brain volume and poorer scores on episodic-memory tests than people who drank less than one a day. Daily fruit-juice intake was also associated with lower hippocampal volume — the hippocampus is the brain region most closely tied to forming new memories.
[2]Researchers are still working out why. Reviews of the research suggest that diets high in added sugar may affect hippocampus-dependent memory, and inflammation is one of the mechanisms being investigated.
[3] "Cutting sweetened drinks is one of the simplest changes a patient can make," Dr. Morita says.
2
Alcohol — Even "Moderate" Amounts
This is the one that surprises patients most. "For a generation, people were told a glass of red wine was good for them," says Dr. Y. Hirano, a neurologist in Tokyo. "The brain-imaging research tells a different story."
A study published in
The BMJ followed 550 adults in the U.K. for 30 years. Higher alcohol intake was associated with greater odds of hippocampal atrophy in a dose-dependent way: people drinking 14–21 units a week had about three times the odds of right-sided hippocampal atrophy compared with non-drinkers, and light drinking showed no protective effect.
[4] A larger analysis of more than 36,000 adults in the UK Biobank found that the link between drinking and lower brain volume was already visible at an average of one to two alcohol units a day.
[5]
3
Diet Sodas and Other Artificially Sweetened Drinks
The third item surprises people who switched to "diet" versions to be healthier. In the Framingham Heart Study, researchers followed 1,484 adults over age 60 for ten years. Those who drank artificially sweetened soft drinks every day had a higher risk of developing dementia, including Alzheimer's disease, than those who drank none.
[6]"This is an observational finding. It does not prove that the drinks cause dementia," Dr. Morita notes. "But when patients ask me what to drink instead, the answer is simple: water, or tea without sugar or sweeteners."
What Major Okafor Had in Common With Them
When Major Okafor's doctor reviewed this list with him during a routine visit, Okafor was quiet for a moment.
"Never been a drinker. Cut soda out completely in my forties — felt foggy after it, even then. Never liked the diet stuff either." He looked up. "I wasn't being strategic. It just didn't feel good."
His physician has noticed similar habits among several of her older patients. "The charts say ordinary," she says. "The minds are remarkable. And when you look at what these patients eat and drink, the differences from the general population are hard to miss."
"The question isn't only what to add to your routine after 60. The more important question might be what to stop putting in."
— Dr. K. Morita
Dr. Morita is careful about his conclusions. Memory is shaped by many factors that drinks alone cannot address. The 2024 report of the Lancet Commission on dementia identified 14 modifiable risk factors — among them physical inactivity, high blood pressure, untreated hearing loss, social isolation, and excessive alcohol use — and estimated that addressing them could prevent or delay nearly half of dementia cases.[7]
"By the time most patients come to me with concerns about memory, the habits have been in place for decades," he says. "Changing them early is best. But the brain can still adapt later in life." That is consistent with research: in a randomized trial of 120 older adults, one year of aerobic exercise increased the size of the hippocampus by about 2% and improved spatial memory.[8]
What Else Researchers Are Studying
Beyond changing what they drink, many older adults are interested in non-drug ways to stay sharp, and two areas have peer-reviewed support. In the ACTIVE trial, older adults who completed ten sessions of reasoning or speed-of-processing training still showed benefits in those specific abilities ten years later.[9] And in a small study of adults aged 60 to 84, short sound pulses played during deep sleep enhanced slow-wave sleep activity and improved overnight memory retention.[10]
"I am not in the business of making promises," Dr. Morita says. "These are early findings, and results vary from person to person. But they are worth knowing about."
For anyone over 60 who has noticed that names take longer to surface, or that thinking feels "slower" than it once did, the message from these physicians was consistent — and it is a good conversation to have with your own doctor:
Start by looking at what you drink.
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References
- Willcox BJ, Willcox DC, Todoriki H, et al. Caloric restriction, the traditional Okinawan diet, and healthy aging: the diet of the world's longest-lived people and its potential impact on morbidity and life span. Ann N Y Acad Sci. 2007;1114:434-455. https://pubmed.ncbi.nlm.nih.gov/17986602/
- Pase MP, Himali JJ, Jacques PF, et al. Sugary beverage intake and preclinical Alzheimer's disease in the community. Alzheimers Dement. 2017;13(9):955-964. https://pubmed.ncbi.nlm.nih.gov/28274718/
- Beilharz JE, Maniam J, Morris MJ. Diet-induced cognitive deficits: the role of fat and sugar, potential mechanisms and nutritional interventions. Nutrients. 2015;7(8):6719-6738. https://pubmed.ncbi.nlm.nih.gov/26274972/
- Topiwala A, Allan CL, Valkanova V, et al. Moderate alcohol consumption as risk factor for adverse brain outcomes and cognitive decline: longitudinal cohort study. BMJ. 2017;357:j2353. https://pubmed.ncbi.nlm.nih.gov/28588063/
- Daviet R, Aydogan G, Jagannathan K, et al. Associations between alcohol consumption and gray and white matter volumes in the UK Biobank. Nat Commun. 2022;13(1):1175. https://pubmed.ncbi.nlm.nih.gov/35246521/
- Pase MP, Himali JJ, Beiser AS, et al. Sugar- and artificially sweetened beverages and the risks of incident stroke and dementia: a prospective cohort study. Stroke. 2017;48(5):1139-1146. https://pubmed.ncbi.nlm.nih.gov/28428346/
- Livingston G, Huntley J, Liu KY, et al. Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission. Lancet. 2024;404(10452):572-628. https://pubmed.ncbi.nlm.nih.gov/39096926/
- Erickson KI, Voss MW, Prakash RS, et al. Exercise training increases size of hippocampus and improves memory. Proc Natl Acad Sci U S A. 2011;108(7):3017-3022. https://pubmed.ncbi.nlm.nih.gov/21282661/
- Rebok GW, Ball K, Guey LT, et al. Ten-year effects of the Advanced Cognitive Training for Independent and Vital Elderly cognitive training trial on cognition and everyday functioning in older adults. J Am Geriatr Soc. 2014;62(1):16-24. https://pubmed.ncbi.nlm.nih.gov/24417410/
- Papalambros NA, Santostasi G, Malkani RG, et al. Acoustic enhancement of sleep slow oscillations and concomitant memory improvement in older adults. Front Hum Neurosci. 2017;11:109. https://pubmed.ncbi.nlm.nih.gov/28337134/